Black Box AI?
Not in BioMedicine.
We help researchers accelerate discoveries with connected biomedical knowledge
Born from a decade of research at UCSF,
SPOKE is a "database of databases" that integrates 80+ disparate biomedical sources into a single, synchronized knowledge graph. By connecting the dots between millions of concepts—from the molecular (genes/proteins) to the phenotypic (symptoms/diseases)—it provides a holistic map of human biology.
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Leveraging our proprietary algorithms, SPOKE eliminates the "Black Box" of traditional AI. It allows researchers to instantly cross disciplines, interpreting complex data in a multi-domain fashion to reveal the specific biological pathways driving discovery.
Explainable AI
SPOKE's connections are scientifically traceable. making it trustworthy for regulatory approval
Industry-Proven
Our solutions are backed by 10+ years of experience and a proven track record of success in pharma and biotech and are used by leading organizations like Pfizer, NASA, and Sanofi​.
Depth & Breath
Over 70 curated databases across genomics, proteomics, toxicology, EHRs, and more, compared to others that rely on noisy, unverified literature
Experts Curation
Over 80 curated databases across genomics, proteomics, toxicology, EHRs, and more, compared to others that rely on noisy, unverified literature
Companies and Organizations that Trusted MateBio
Working with the Best Partners
