Our Story
MateBio originated as a University of California San Francisco (UCSF) spin-off aimed at harnessing the power of SPOKE.
Our Mission is to support academic, clinical, and pharmaceutical researchers in understanding diseases and biological complexity better and bringing new products to the market faster.
Our Technology
At the core of Mate’s technology is the Scalable Precision Medicine Knowledge Engine (SPOKE), a “database of databases” that integrates existing biomedical knowledge into a graph database developed at UCSF.
The scope of SPOKE is unlike any graph currently available to consumers. It intelligently brings together information at the smallest (molecular) to largest (phenotypic) levels. Together with our proprietary algorithms, it crosses disciplines to instantly bring researchers the information they need and interpret their data in a multi-domain fashion.
At Mate Bio, we recognize the challenges of navigating the vast and complex landscape of biomedical data. Traditional approaches have struggled to connect the dots and unlock the full potential of this information.
Our multidisciplinary team of physicians, biochemists, pharmacologists, drug developers, and computer scientists takes a different approach. We start with a deep understanding of the underlying biological mechanisms and design our systems with the user in mind.
This unique expertise allows us to support our partners in their research and drug development efforts by speaking their language and providing intuitive tools that translate complex data into actionable insights.
Our Approach
Our Leadership Team
Charlotte Nelson, PhD
Chief Scientific Officer
Designer of Mate proprietary algorithms and SPOKE-EHR applications. Expert in knowledge graphs, AI & ML, systems biology, and structural biology.
Deb Pandra
Chief Executive Officer
Driving software innovation, team, and business excellence for over 15 years. Experienced entrepreneur and intrapreneur with a strong customer focus. Expertise in product strategy, development, and operations. Passionate about building and scaling disruptive products that make a difference.
Gustavo Mahler, PhD
Founder & Board Member
Managing Partner at Dynamk Capital, CEO at AGC Biologics (former CMC Biologics), VP of Operations at Bayer HealthcareManaging Partner at Dynamk Capital, CEO at AGC Biologics (former CMC Biologics), VP of Operations at Bayer Healthcare.
Sergio Baranzini, PhD
Founder & Board Member
Distinguished Professor of Neurology at the University of California San Francisco (UCSF). Expert in systems biology, genetics, complex systems, and knowledge representation.
Ezequiel Actis Grosso
Chief Technology Officer
Carlos Gonzalez
Chief Financial Officer
Ignacio Garcia Labari
Senior Bioinformatician
Samuel Acosta
Senior Bioinformatician
Our Advisory Board
Keith Yamamoto, PhD
UCSF
Professor, Cellular Molecular Pharmacology
Vice Chancellor for Science Policy and Strategy
Director, UCSF Precision Medicine
Leroy Hood, MD, PhD
ISB
Co-founder, Professor and Chief Strategy Officer, ISB; Emeritus Science Advisor, Providence
Eric Schadt, PhD
Sema4, Mount Sinai
Founder/CEO Sema4, Dean for Precision Medicine and Professor at Mount Sinai, Board Member/Co-Founder Sage Bionetworks, previously CSO Pacific Biosciences