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BINDS_CbP

Last Updated

Current

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node_web_buttons_proteindomain copy 2.png

Description

A causal mechanism mediated by the direct contact between a compound and a protein, which form a stable physical interaction.

Properties

  • bindingdb_ic50s - The half maximal inhibitory concentration(s) (nM)

  • bindingdb_k - Affinity calculated by preferentially selecting Kd over Ki over IC50 and taking a geometric mean when there were multiple measurements of the same measure

  • bindingdb_kds - The equilibrium dissociation constant(s) (nM)

  • bindingdb_kis - The inhibitory constant(s) (nM)

  • bindingdb_sources - Source(s) on BindingDB

  • bindingdb_urls - Link(s) to BindingDB results

  • chembl_action_type - ACTIVATOR, AGONIST, ANTAGONIST, ANTISENSE INHIBITOR, BINDING AGENT, BLOCKER, CROSS-LINKING AGENT, INHIBITOR, INVERSE AGONIST, MODULATOR, NEGATIVE ALLOSTERIC MODULATOR, OPENER, OTHER, PARTIAL AGONIST, POSITIVE ALLOSTERIC MODULATOR, POSITIVE MODULATOR, PROTEOLYTIC ENZYME, RELEASING AGENT, STABILISER, or SUBSTRATE 

  • drugcentral_relationship - ACTIVATOR, AGONIST, ALLOSTERIC ANTAGONIST, ALLOSTERIC MODULATOR, ANTAGONIST, ANTIBODY BINDING, ANTISENSE INHIBITOR, BINDING AGENT, BLOCKER, GATING INHIBITOR, INHIBITOR, INVERSE AGONIST, MODULATOR, NEGATIVE ALLOSTERIC MODULATOR, OPENER, PARTIAL AGONIST, PHARMACOLOGICAL CHAPERONE, POSITIVE ALLOSTERIC MODULATOR, POSITIVE MODULATOR, RELEASING AGENT, SUBSTRATE, unspecified (DrugCentral)

  • sources - Original data source(s)

Updates

V5        840,047 edges

V4        870,961 edges

V3        873,942 edges

V2        873,942 edges

V1        899,252 edges

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