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Description
A causal mechanism mediated by the direct contact between a compound and a protein, which form a stable physical interaction.
Properties
bindingdb_ic50s - The half maximal inhibitory concentration(s) (nM)
bindingdb_k - Affinity calculated by preferentially selecting Kd over Ki over IC50 and taking a geometric mean when there were multiple measurements of the same measure
bindingdb_kds - The equilibrium dissociation constant(s) (nM)
bindingdb_kis - The inhibitory constant(s) (nM)
bindingdb_sources - Source(s) on BindingDB
bindingdb_urls - Link(s) to BindingDB results
chembl_action_type - ACTIVATOR, AGONIST, ANTAGONIST, ANTISENSE INHIBITOR, BINDING AGENT, BLOCKER, CROSS-LINKING AGENT, INHIBITOR, INVERSE AGONIST, MODULATOR, NEGATIVE ALLOSTERIC MODULATOR, OPENER, OTHER, PARTIAL AGONIST, POSITIVE ALLOSTERIC MODULATOR, POSITIVE MODULATOR, PROTEOLYTIC ENZYME, RELEASING AGENT, STABILISER, or SUBSTRATE
drugcentral_relationship - ACTIVATOR, AGONIST, ALLOSTERIC ANTAGONIST, ALLOSTERIC MODULATOR, ANTAGONIST, ANTIBODY BINDING, ANTISENSE INHIBITOR, BINDING AGENT, BLOCKER, GATING INHIBITOR, INHIBITOR, INVERSE AGONIST, MODULATOR, NEGATIVE ALLOSTERIC MODULATOR, OPENER, PARTIAL AGONIST, PHARMACOLOGICAL CHAPERONE, POSITIVE ALLOSTERIC MODULATOR, POSITIVE MODULATOR, RELEASING AGENT, SUBSTRATE, unspecified (DrugCentral)
sources - Original data source(s)